Product ID:NEOMYCIN SULFATE, N1876
MSDS Date:07/01/1999
FSC:6505
NIIN:01-371-5045
Status Code:A
MSDS Number: CJQPQ

Emergency Phone: 314-771-5765

Info Phone: 314-771-5765

Cage: 21076

Telephone: 314-771-5765

Cage: 21076

(ORAL,RAT) >4325 MG/KG (SUPPLIER

CAS: 1405-10-3

RTECS: QP4375000

ACGIH TLV: 2 MG/M3 TWA

LD50 LC50 Mixture:SEE INGREDIENTS & TOX INFORMATION.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE: MAY BE HARMFUL BY INHALATION,
INGESTION OR SKIN ABSORPTION. CAUSES EYE AND SKIN IRRITATION.
MATERIAL IS IRRITATING TO MUCOUS MEMBRANES AND UPPER RESPIRATORY
TRACT. MAY CAUSE ALLERGIC RESPIRATOR Y AND SKIN REACTIONS. CHRONIC:
POSSIBLERISK OF CONGENITAL MALFORMATION IN THE FETUS. TARGET
ORGAN(S): KIDNEYS, EARS. TO THE BEST OF MFR'S KNOWLEDGE, THE
CHEMICAL, PHYSICAL AND TOXICOLOGICAL PROPERTIES HAVE NOT BEEN
THOROUGHLY INVESTIGATED. TARGET ORGAN DATA: SENSE ORGANS AND
SPECIAL SENSES (CHANGE IN ACUITY); BEHAVIORAL (CONVULSIONS OR
EFFECT ON SEIZURE THRESHOLD).
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:EYES: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER FOR AT
LEAST 15 MINUTES. SKIN: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF
WATER FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING
AND SH OES. WASH CONTAMINATED CLOTHING BEFORE REUSE. INHALATION:
REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL RESPIRATION.
IF BREATHING IS DIFFICULT, GIVE OXYGEN. INGESTION: WASH OUT MOUTH
WITH WATE R PROVIDE PERSON IS CONSCIOUS. CALL MD.

Extinguishing Media:WATER SPRAY, CARBON DIOXIDE, DRY CHEMICAL POWDER OR
APPROPRIATE FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT .
Unusual Fire/Explosion Hazard:EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:EVACUATE AREA. WEAR NIOSH APPROVED
SELF-CONTAINED BREATHING APPARATUS, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. WEAR DISPOSABLE COVERALLS AND DISCARD THEM AFTER USE. SWEEP
UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID RAISING
DUST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS
COMPLETE.

Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
KEEP TIGHTLY CLOSED. STORE IN A COOL, DRY PLACE.
Other Precautions:HARMFUL. POSSIBLE RISK OF HARM TO THE UNBORN CHILD.
MAY CAUSE SENSITIZATION BY INHALATION AND SKIN CONTACT. IRRITATING
TO EYES, RESPIRATORY SYSTEM AND SKIN. IN CASE OF ACCIDENT OR IF YOU
FEEL UNWELL, SEEK MEDICAL ADVICE IMMEDIATELY (SHOW LABEL WHERE
POSSIBLE).

Respiratory Protection:WEAR APPROPRIATE NIOSH APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES & FULL LENGTH
FACESHIELD .
Other Protective Equipment:ANSI APPROVED EYE WASH & DELUGE SHOWER .
WEAR OTHER SUITABLE PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
PHYSICAL DATA: SOLUBILITY: IN ETHER - INSOLUBLE; IN ETHANOL - SLIGHTLY
SOLUBLE; IN ACETONE - INSOLUBLE.

Solubility in Water:SOLUBLE
Appearance and Odor:SOLID.

Stability Indicator/Materials to Avoid:YES
STRONG OXIDIZING AGENTS.
Stability Condition to Avoid:HEAT. MAY DECOMPOSE ON EXPOSURE TO LIGHT.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE, NITROGEN OXIDES, SULFUR OXIDES.
Conditions to Avoid Polymerization:WILL NOT OCCUR.

Waste Disposal Methods:DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE
SOLVENT AND BURN IN A CHEMICAL INCINERATOR EQUIPPED WITH AN
AFTERBURNER AND SCRUBBER. OBSERVE ALL FEDERAL, STATE AND LOCAL
ENVIRONMENTAL REGULATIONS.

Toxicological Information:AMINOGLYCOSIDES ARE ASSOC W/SIGNIFICANT
NEPHROTOXICITY &/OR OTOTOXICITY. IRRIT DATA: SKIN-HMN 6 MG/3D-I MLD
- 85DKA8 -,127,1977. TOX DATA: LD50:(SCU,RAT) 200 MG/KG - ARZNAD
12,597,1962. LD50:(ORAL,MUS ) >8 GM(BASE)/KG - AACHAX -,138,1963.
LD50:(IPR,MUS) 305 MG/KG - ANTCAO 8,198,1958. LD50:(SCU,MUS) 190
MG/KG - ANTBAL 18,444,1973. LD50:(IVN,MUS) 17400 UG/KG - AITEAT
10,947,1962. LD50:(IMS,MUS) 142 M G/KG - AIMDAP 119,493,1967.
LD50:(ICE,MUS) 32 MG/KG - TXAPA9 7,361,1965. LD50:(IMS,GPG) >250
MG/KG - TXAPA9 33,320,1975. ONLY SELECTED RTECS DATA IS PRESENTED
HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPL ETE INFO.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:DATA NOT YET AVAILABLE.

Transport Information:CONTACT SIGMA CHEMICAL COMPANY FOR TRANSPORTATION
INFORMATION.

Federal Regulatory Information:EUROPEAN INFO: HARMFUL R 63 - POSS RISK
OF HARM TO UNBORN CHILD. R 42/43 - MAY CAUSE SENSIT BY INHAL & SKIN
CONT. R 36/37/38 - IRRIT TO EYES, RESP SYS & SKIN. S 45 - IN CASE
OF ACCIDENT/IF YOU FEEL UN WELL, SEEK MED ADVICE IMMED (SHOW LBL
WHERE POSS). S 26 - IN CASE OF CONT W/EYES, RINSE IMMED W/PLENTY OF
WATER & SEEK MED ADVICE. S 36/37/39 - WEAR SUITABLE PROT CLTHG,
GLOVES & EYE/FACE PROT. REVIEW S, STDS & REGS: OEL=MAK. EPA FIFRA
1988 PESTICIDE SUBJECT TO REGISTRATION/RE-REGISTRATION FEREAC 54,
7740,1989. NOES 1983: HZD X3700; NIS 23; TNF 3566; NOS 33; TNE
180078; TFE 143663. NOES 1983: HZD X9498; NIS 5; TNF 1014; (OTHER
INFO)
State Regulatory Information:CALIFORNIA PROPOSITION 65: THIS PRODUCT IS
OR CONTAINS CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE
DEVELOPMENTAL TOXICITY.